Electronic symptom monitoring (ESM) refers to symptom monitoring relying on electronic systems via the World Wide Web, a smartphone app, or an automated telephone interface. ESM systems are evaluated symptom reporting systems that collect the symptom data remotely and are used to communicate symptoms between patients and healthcare providers in a clinical consultation, thereby potentially influencing clinical decision-making. The innovation in ESM overcomes several challenges of former symptom monitoring methods to provide real-time rather than retrospective feedback from any internet-accessible device.

In this review, we want to find a clinical expert who has ever participate in large-scale randomized controlled trials of ESM to help us improve the clinical significance of our review.